Designed Proteins Are Leaving the Lab. The Validation Gap Is Widening.
Computational design now produces candidate binders in days. Experimental characterisation still takes months, and the backlog is changing which claims get published.
Section
Peer-reviewed research explained without the hype, plus the messier story of how it gets funded, replicated, and occasionally retracted. Space, physics, biology, and the instruments that make discovery possible.
2 articles in this section
Computational design now produces candidate binders in days. Experimental characterisation still takes months, and the backlog is changing which claims get published.
Automated transient detection found substantially more core-collapse events than models predicted, and the discrepancy is largest exactly where dust obscures the view.